Disorders by Phi

Puzzle explanation

Extra letters in wordplay gave “personalised diseases”, that is, diseases named after specific people (generally physicians), eight examples of which were to be highlighted in the final grid: Cushing, Lou Gehrig, Addison, Paget, Kawasaki, Bright, Pott and Alzheimer. Jumbled entries, Across: 4 astonishing 13 hour-angle 14 addios 16 biotic 21 gate 22 waka 29 intuit 32 renascent 33 puzzle-heads 34 mire; Down: 5 noria 6 lang 9 Shiah 20 broth 26 zack 28 hide.

Clue explanations

Conventions: * = anagram, < = reversal

No Extra
Letter		 Answer Explanation
Across
1 P CUSH C + PUSH
4   ASTONISHING A + SING about TONISH
13   HOUR-ANGLE (U + RANG) in HOLE
14   ADDIOS ADD + IS about O
15 E TAHITI (IT + I + HEAT) <
16   BIOTIC BI (Chinese) + CITO <
19 R APOOP A + POOR + P
21   GATE (risin)G + ATE
22   WAKA WAK(e) + A
24 S SAKIA Two definitions (SASKIA, a Dutch name)
27 O RUSSIA RU + OSSIA (musical term)
29   INTUIT INUIT about T
30 N BRIGHT NB + RIGHT
32   RENASCENT ASCEN(d) in RENT
33   PUZZLE-HEADS PUZZLE (see pucelle) + HEADS
34   MIRE M + IRE
Down
1 A CRACKUPS UP in CARACKS
2 L UNDO U + INDOL – I
3 I SAD DAIS <
4 S INSISTED (I’S + TED) after (seven deadly) SINS
5   NORIA NORI + A
6   LANG (c)LAN + G(rieve)
7 E OUZO OU + ZOE; we apologise for the faulty definition: “liqueur” would be more accurate
8 D SEA PURSE ((DEEP AS US) + R) *
9   SHIAH SHAH about I
10 D TRIGS DIRT < + G(ood) + S(olid)
11 I SITE IS IT E?
12 S AGITATOR A + GIT + AS TO + R
17 E TWITE (WIT about TEE) in reverse
18 A BANTU MANTUA, M to B
20   BROTH (B + H) about ROT
23 S ATOP A + STOP
25 E KORA Two definitions (KOREA)
26   ZACK Two definitions, one a shortened name
28   HIDE Two definitions (FELL = SKIN)
31 S GEM (S&M + EG) <
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